Cannabidiol or CBD, for short, is one of over 80 active compounds phytocannabinoids or plant-based cannabinoids found in the cannabis plant. CBD is present in medical and recreational cannabis, as well as in medicinal and industrial cultivars of hemp. CBD was the first phytocannabinoid discovered. This discovery was made by a chemist named Roger Adams in 1940. Though Adams discovered CBD, he wasn’t aware of the significance of this find.
Raphael Mechoulam was working on the study of cannabis in the early ’60s. In 1964 along with his team of researchers, Mr. Mechoulam was accredited as the first to isolate and describe the chemical composition of CBD. From here, science explored the avenues of potential benefits that CBD may provide. Studies, along with a growing number of consumer reports, all point to positive signs supporting CBD as a medicine.
Forms of CBD
CBD is available in several different forms. There are CBD flower options rich in CBD and THC. There are also CBD flower options rich in CBD and absent of THC. CBD products available on the Australian Register of Therapeutic Goods for approved patients include oral & spray applications, capsules, cream & patch applications and dried flower deliveries.
CBD products are not all created equal, either. There is the option of choosing CBD products made from CBD isolate, which are made from 99% pure CBD or Full Spectrum CBD, which has CBD along with other cannabinoids like CBG and CBN and terpenes. Both have different use cases and to find out what works best for you, it’s best to consult with a medical practitioner.
Science of CBD with ECS
Cannabinoids like CBD work synergistically with the mammalian endocannabinoid system (ECS)to help the body in a magnitude of different ways. One of these ways is by helping the body to achieve and maintain homeostasis, meaning bringing balance to some of our body’s regulatory systems that cause stress, like inflammation, pain, and more.
CBD works with the ECS but has very little binding affinity to CB1 and CB2 receptors. CBD also works with another group called THRV receptors along with other pathways in the body, such as oxygenian pathways.
Unlike tetrahydrocannabinol (THC) – the other primary and most known cannabinoids in cannabis, CBD doesn’t cause a euphoric or intoxicating reaction. In other words, CBD won’t get you high.
Clinical Trials in Support of CBD
Although many claim CBD to be a panacea for a host of conditions and symptoms, it’s important to remember that research is still in its infancy stage and CBD can interact with a wide range of prescribed medications. It is important that you consult a healthcare practitioner before Current evidence suggest that CBD can increase anandamide and neurotransmitter serotonin, showing the potential to assist the body in dealing with stress and working as an anti-inflammatory compound.
You can read multiple clinical research papers supporting the therapeutic benefits of CBD on accredited websites such as ANZCTR. Many studies show promising results regarding the medicinal qualities found in CBD. Below you can find a list of several CBD clinical trials currently underway in Australia.
- The effect of cannabidiol on simulated car driving performance
- An open label study to evaluate the safety of Cannabidiol (CBD) for the prevention of Acute Graft-Versus-Host Disease (GVHD) after allogeneic hematopoietic cell transplantation
- A study to evaluate the effect of food on the pharmacokinetics and cardiac function in male and female healthy volunteers who have been administered cannibidiol.
- Cannabinoids for Symptom Control in Advanced Cancer, an Open Label Prospective Clinical Trial in New South Wales (NSW)
- Pediatric Epilepsy clinical trial via the Compassionate Access Scheme
How to obtain medical CBD in Australia?
Cannabis and its derivatives are substances included in Schedule 4 and Schedule 8 of the Poisons Standard. When a medicine falls into a Schedule 4 substance the medicine is more commonly known as a prescription medicine and Schedule 8 substances are controlled drugs, both of which can only be supplied on prescription.
To obtain any cannabis products legally within Australia, you will need to qualify and be approved through a clinical trial, or through either the Special Access Scheme or the Authorised Prescriber Scheme. Once approved, you will also need to obtain a prescription from a medical practitioner to have your product legally dispensed from a Pharmacy. To learn more about the process, book an appointment with one of our nurses for a consultation.